MicroRNA MIMIC binding sites: Minor flanking nucleotide alterations can strongly impact MIMIC silencing efficacy in Arabidopsis
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چکیده
منابع مشابه
MicroRNA-Target Binding Structures Mimic MicroRNA Duplex Structures in Humans
Traditionally, researchers match a microRNA guide strand to mRNA sequences using sequence comparisons to predict its potential target genes. However, many of the predictions can be false positives due to limitations in sequence comparison alone. In this work, we consider the association of two related RNA structures that share a common guide strand: the microRNA duplex and the microRNA-target b...
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ژورنال
عنوان ژورنال: Plant Direct
سال: 2018
ISSN: 2475-4455
DOI: 10.1002/pld3.88